Overview

Visual Ease is formulated to support daily eye health, visual comfort, and antioxidant protection — especially for modern screen-driven lifestyles. Below is a curated list of peer-reviewed studies and academic references related to key nutrients commonly researched for macular pigment support, oxidative balance, dry eye, and digital eye strain.

References

  1. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS Report No. 8. Arch Ophthalmol. 2001. PMID: 11594942.
  2. Chew EY, et al. Long-term outcomes of adding lutein/zeaxanthin and ω-3 fatty acids to the AREDS supplements on age-related macular degeneration progression: AREDS2 Report 28. JAMA Ophthalmol. 2022.
  3. Evans JR, Lawrenson JG. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane Database Syst Rev. 2023. doi:10.1002/14651858.CD000254.pub5.
  4. Hammond BR Jr, Fletcher LM, Roos F, Wittwer J, Schalch W. A double-blind, placebo-controlled study on the effects of lutein and zeaxanthin on photostress recovery, glare disability, and chromatic contrast. Invest Ophthalmol Vis Sci. 2014;55(12):8583-8589. doi:10.1167/iovs.14-15573. PMID: 25468896.
  5. Lopresti AL, et al. The effects of lutein/zeaxanthin supplementation on eye health outcomes in regular electronic screen users: a randomized controlled trial. Frontiers in Nutrition. 2025.
  6. Ozawa Y, et al. Bilberry extract supplementation for preventing eye fatigue induced by acute video display terminal loads: a randomized, double-blind, placebo-controlled study. J Nutr Health Aging. 2015. PMID: 25923485.
  7. Nakaishi H, et al. A 12-week-long intake of bilberry extract (Vaccinium myrtillus L.) improved objective findings of ciliary muscle contraction of the eye: a randomized, double-blind, placebo-controlled trial. Nutrients. 2020.
  8. Fan M, et al. Anthocyanin oligomer (grape skin extract) administration improves dry eye disease: a randomised, double-blind, placebo-controlled study. Clin Exp Ophthalmol. 2023;51(2):122-130. doi:10.1111/ceo.14207. PMID: 36703096.
  9. Kapil D, et al. Role of oral bio-enhanced curcumin in dry eye disease: a randomized, double-masked, placebo-controlled study. 2025.
  10. McKay TB, Karamichos D. Quercetin and the ocular surface: what we know and where we are going. Exp Eye Res. 2017. PMCID: PMC5685256.
  11. Johra FT, Bepari AK, Bristy AT, Reza HM. A mechanistic review of β-carotene, lutein, and zeaxanthin in eye health and disease pathways. Nutrients. 2020. PMCID: PMC7692753.
  12. Kaur K, Gurnani B, Nayak S. Digital eye strain: a comprehensive review. Ophthalmol Ther. 2022. PMCID: PMC9434525.
  13. Orobia AJM. A narrative literature review about alpha-lipoic acid role in ocular surface disorders and dry eye disease. 2025. PMID: 40207422.

Disclaimer

These references are provided for informational and educational purposes only. Visual Ease is a dietary supplement, not a drug. The studies cited relate to individual ingredients or nutrient categories and do not evaluate Visual Ease as a finished product. Individual results may vary.